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  • TRP-Mediated Signaling
    TRP-Mediated Signaling

    The field of transient receptor potential (TRP) channels has gained momentum in recent years not only because of the 2021 Nobel Prize in Physiology or Medicine awarded to David Julius and Ardem Patapoutian for their discoveries of receptors for temperature and touch, but also because of the growing appreciation of the diverse and important physiological and pathophysiological functions of this diverse family of cation channels.In the past decade, there have been important discoveries in the TRP field: resolution of the 3-D structures of major subfamilies using single-particle cryogenic electron microscopy and X-ray crystallography, identification and development of selective agonists and antagonists for most TRP subfamily members, discovery of new human diseases associated with TRP gene mutations, as well as improved understanding of TRP channel function and regulation in various systems.These new discoveries are addressed in TRP-Mediated Signaling, a volume in the Methods in Signal Transduction book series. Key Features• Summarizes recent advances in the study of TRP channels• Written by a team of leading international researchers• Reviews physiological and pathophysiological functions of TRP channels• Identifies diseases associated with TRP gene mutations• Examines the evolution of temperature-sensing TRP channels

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  • Encyclopedia of Signaling Molecules
    Encyclopedia of Signaling Molecules

    The second edition of this encyclopedia presents about 1000 chapters and includes thousands of biologically important signaling molecules and the content is built on the core concepts of their functions along with early findings written by some of the world’s foremost experts.The molecules are described by recognized leaders in each molecule.The interactions of these single molecules in signal transduction networks will also be explored.This encyclopedia marks a new era in overview of current cellular signaling molecules for the specialist and the interested non-specialist alike. Currently, there are more than 30,000 genes in human genome.However, not all the proteins encoded by these genes work equally in order to maintain homeostasis.Understanding the important signaling molecules as completely as possible will significantly improve our research-based teaching and scientific capabilities.

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  • Signaling System #7, Sixth Edition
    Signaling System #7, Sixth Edition

    Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. THE MOST COMPLETE, CURRENT GUIDE TO SIGNALING SYSTEM #7 (SS7)Thoroughly updated to cover the latest advances in the telecommunications industry, Signaling System # 7, Sixth Edition, addresses the impact of emerging technologies and applications, such as Long Term Evolution (LTE) and 4G networks, on SS7.An all-new chapter onDiameter discusses how to successfully implement SS7-to-Diameter interfaces to bridge 3G and 4G networks.Real-world examples, protocol message details, call flows, and effective migration strategies are included in this practical guide. Comprehensive coverage includes:The SS7 network--international and national planesThe OSI modelSS7 protocols and the protocol stackSignal unitsMessage Transfer Part (MTP), including level 3Signaling Transport (SIGTRAN)ISDN User Part (ISUP)Signaling Connection Control Part (SCCP)Transaction Capabilities Application Part (TCAP)The evolution to Diameter

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  • Signaling by Receptor Tyrosine Kinases
    Signaling by Receptor Tyrosine Kinases


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  • What are hydrophilic signaling molecules?

    Hydrophilic signaling molecules are molecules that are able to dissolve in water and interact with water molecules. These molecules are often involved in cell signaling and communication within the body. They can bind to specific receptors on the surface of cells, triggering a series of biochemical reactions that ultimately lead to a cellular response. Examples of hydrophilic signaling molecules include hormones like insulin and adrenaline, as well as neurotransmitters like serotonin and dopamine.

  • What is the signaling rate of DPI?

    The signaling rate of DPI (Deep Packet Inspection) can vary depending on the specific hardware and software being used. However, in general, DPI technology is capable of processing and inspecting network traffic at very high speeds, often reaching rates of multiple gigabits per second. This high signaling rate allows DPI to efficiently analyze and classify network packets in real-time, enabling it to identify and respond to various types of traffic patterns and threats.

  • How is the signaling of lovers done?

    The signaling of lovers is often done through a combination of verbal and nonverbal communication. Verbal signals can include expressions of affection, declarations of love, and the use of pet names. Nonverbal signals can include physical touch, eye contact, and body language that conveys intimacy and connection. Additionally, lovers may use gestures, gifts, and acts of service to communicate their feelings for each other. Overall, the signaling of lovers is a complex and nuanced process that involves both explicit and subtle forms of communication.

  • Should one look into all mirrors before signaling?

    Yes, it is important to look into all mirrors before signaling. Checking all mirrors allows you to be aware of your surroundings and any potential hazards, such as other vehicles or pedestrians. This helps ensure that you can safely change lanes or make a turn without causing an accident. By being diligent in checking all mirrors before signaling, you can be a responsible and considerate driver on the road.

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  • Kisspeptin Signaling in Reproductive Biology
    Kisspeptin Signaling in Reproductive Biology

    Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis.Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress.This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis.

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  • Cell Signaling in Model Plants 2.0
    Cell Signaling in Model Plants 2.0

    Plant cell signaling is an intensive research topic in which reductionism can be achieved when we investigate the systems of model plants. To continue our previous book entitled "Cell Signaling in Model Plants", the second volume explores more insights into the regulatory mechanisms of plant growth and development and eventually collects 20 publications that consist of one editorial, eleven original research articles and eight literature reviews. This book only presents a snapshot of this intensive field of plant biology, and we believe that with the rapid development of advanced technology such as integrative multi-omics and CRISPR genome editing, more and more critical networks of plant cell signaling will be unraveled in the future.

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  • Plant Ionomics : Sensing, Signaling and Regulation
    Plant Ionomics : Sensing, Signaling and Regulation

    Plant Ionomics A thoroughly up-to-date exploration of nutrient uptake in plants In Plant Ionomics: Sensing, Signaling and Regulation, accomplished botanists and researchers Dr. Vijay Singh and Dr. Manzer Siddiqui deliver an up-to-date discussion on the sensing, signaling, and regulation of nutrient uptake in plants under a variety of conditions.The book offers an accessible and easy-to-use reference for researchers with an interest in plant ionomics, combining the latest research from leading laboratories around the globe.The authors provide coverage of a variety of critical topics, including plant and soil nutrient stoichiometry, nutrient management and stress tolerance in crops, and the relationship between agricultural production and nutrient applications.Readers will also find: A thorough introduction to nutrient regulation and abiotic stress tolerance in plantsIn-depth discussions of nutrient uptake and transport in plants and the role of nutrients in ROS metabolismPractical explorations of nutrient and sugar signaling and associated gene networks in plantsExtensive treatments of the role of nutrients in plant–microbe interactions and nutrient-use efficiency in plants Perfect for students, researchers, academics, and scientists with an interest in plant nutrition, Plant Ionomics: Sensing, Signaling and Regulation will also earn a place in the libraries of professionals in the agriculture and pharmaceutical industries.

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  • Emergency light stick for position signaling
    Emergency light stick for position signaling

    For departures on hikes and for camping, remember to have this light stick in your belongings. It will be very useful for indicating your presence in the event of a problem and will also serve as a light.* Dimensions : 4.7 x 1.8 x 1.8cm * Usage time : about 10 to 12 hours * Without battery or battery * One time use * Amount : 1 Functions : light stick Contents : 1 emergency light stick* Dimensions : 4.7 x 1.8 x 1.8cm * Usage time : about 10 to 12 hours * Without battery or battery * One time use * Amount : 1 Functions : light stick Contents : 1 emergency light stick

    Price: 20.19 € | Shipping*: 0.0 €
  • Why does the interior lighting flicker when signaling?

    The interior lighting may flicker when signaling because the turn signal and the interior lights are often connected to the same circuit in a vehicle. When the turn signal is activated, it can cause a temporary increase in electrical load on the circuit, leading to fluctuations in the power supply to the interior lights. This fluctuation can result in the lights flickering momentarily while the turn signal is in use. It is a common occurrence in older vehicles or those with wiring issues.

  • How does the fire department use the signaling disc?

    The fire department uses the signaling disc as a communication tool during emergencies. When responding to a call, firefighters can place the signaling disc in a visible location to indicate their presence and provide information to other emergency responders. The disc can also be used to mark hazards, designate meeting points, or signal specific instructions to the team. Overall, the signaling disc helps improve coordination and communication among firefighters during critical situations.

  • How does a signaling circuit with 3 signals work?

    A signaling circuit with 3 signals typically involves three different input signals that are processed in some way to produce an output signal. Each input signal may carry different information or commands, and the circuit is designed to interpret and combine these signals to generate a specific response. The signals may be processed through logic gates, amplifiers, or other components to determine the appropriate output based on the combination of inputs. This type of circuit is commonly used in control systems, communication networks, and electronic devices to enable complex decision-making and functionality.

  • Should not signaling in traffic be punished more severely?

    Not signaling in traffic can be dangerous and lead to accidents, so it is important to encourage safe driving habits. However, the severity of punishment should be balanced with the actual risk and harm caused by the offense. While not signaling is certainly a violation of traffic laws, it may not always result in immediate danger or harm. Instead of increasing punishment, a better approach may be to focus on education and awareness campaigns to promote the importance of signaling and safe driving practices. This can help to create a culture of responsible driving and reduce the need for more severe punishment.

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